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br Please cite this article in
2020-03-17
Please cite this article in press as: Huang et al., A Systems Pharmacology Approach Uncovers Wogonoside as an Angiogenesis Inhibitor of Triple-Negative Breast Cancer by Targeting Hedgehog Signaling, Cell Chemical Biology (2019), https://doi.org/10.1016/j.chembiol.2019.05.004 significantly highe
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br When repeating the analysis with
2020-03-17
When repeating the analysis with high-purity tumor samples (Figure S2), much of the enrichment of secretome expression increases in ECM-related functions were reduced or absent, indicating a potential contribution of non-tumor Actinomycin D to this behavior. However, significant coordinated expre
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br Gene set variation analysis
2019-11-12
2.6. Gene set variation analysis (GSVA) GSVA is a gene set enrichment method that Luteolin estimates the varia-tion of pathway and biological process activity over a sample popula-tion in an unsupervised manner [31]. The gene set files of “c2.cp. kegg.v6.2.symbols” and “h.all.v6.2.symbols,” do
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Keywords br Rectified factor networks br Biclustering
2019-11-12
Keywords: Rectified factor networks Biclustering Biomarker miRNA Gene-miRNA interaction Breast cancer Detecting cancer-related genes and their interactions is a crucial task in cancer research. For this purpose, we proposed an efficient method, to detect coding genes, microRN
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br IOUS intraoperative ultrasound PPPD
2019-11-11
IOUS = intraoperative ultrasound; PPPD = pylorus preserving pancreatoduodectomy. on preoperative imaging, and in one of these patients, the vascular contact could also not be assessed with IOUS. The analysis revealed that contact (or lack of con-tact) between the tumor and the vascular groov
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Nonetheless in present day cancer research there is a marked
2019-11-05
Nonetheless, in present-day cancer research there is a marked tendency to overlook the role of the immune system. The increase in cancer incidence with age indicates that cancer is the result of a multistep accumulation of cellular changes; if caused by one-step changes, cancer would occur with s
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br composition Abellan Pose et al Although the majority
2019-10-22
composition (Abellan-Pose et al., 2016). Although the majority of the work in the literature describes the intravenous administration of na-noparticles, intratumoural injection (the intended application of our nanocomposite hydrogel) of small NCs locally also has the potential to give increased
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Veratridine br Taking into consideration the advantages
2019-10-21
● Taking into consideration the advantages of IG and GAW, then proposing a IGSAGAW hybrid feature selection approach, which can remove redundant and irrelevant feature from the feature space, thus improving the classification accuracy and reducing the computational cost. ● Taking into considera
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br Fresh frozen GC tissues and corresponding normal gastric
2019-10-21
Fresh-frozen GC tissues and corresponding normal gastric epithelial tissues were collected from 38 patients who underwent tumor surgical resection at The First Affiliated Hospital of Soochow University from May 2015 to May 2018. The study was approved by the ethics com-mittee of The First Affiliated H